Issue 16, 2015

Palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines with isocyanides through double sp2 C–H bonds cleavage: facile synthesis of 4-aminoquinoline derivatives

Abstract

An efficient method for the synthesis of 4-aminoquinolines via palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines and isocyanides through double sp2 C–H bonds cleavage has been developed.

Graphical abstract: Palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines with isocyanides through double sp2 C–H bonds cleavage: facile synthesis of 4-aminoquinoline derivatives

Supplementary files

Article information

Article type
Communication
Submitted
16 Feb 2015
Accepted
11 Mar 2015
First published
11 Mar 2015

Org. Biomol. Chem., 2015,13, 4657-4660

Author version available

Palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines with isocyanides through double sp2 C–H bonds cleavage: facile synthesis of 4-aminoquinoline derivatives

Q. Zheng, P. Luo, Y. Lin, W. Chen, X. Liu, Y. Zhang and Q. Ding, Org. Biomol. Chem., 2015, 13, 4657 DOI: 10.1039/C5OB00329F

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