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Issue 11, 2015
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PhI(OAc)2-mediated functionalisation of unactivated alkenes for the synthesis of pyrazoline and isoxazoline derivatives

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Abstract

A PhI(OAc)2-promoted radical cyclization of β,γ-unsaturated hydrazones and oximes has been developed for an efficient synthesis of various valuable pyrazoline and isoxazoline derivatives with satisfactory yields (up to 96%) under mild conditions.

Graphical abstract: PhI(OAc)2-mediated functionalisation of unactivated alkenes for the synthesis of pyrazoline and isoxazoline derivatives

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Supplementary files

Article information


Submitted
07 Jan 2015
Accepted
30 Jan 2015
First published
30 Jan 2015

Org. Biomol. Chem., 2015,13, 3457-3461
Article type
Paper

PhI(OAc)2-mediated functionalisation of unactivated alkenes for the synthesis of pyrazoline and isoxazoline derivatives

X. Hu, G. Feng, J. Chen, D. Yan, Q. Zhao, Q. Wei and W. Xiao, Org. Biomol. Chem., 2015, 13, 3457
DOI: 10.1039/C5OB00029G

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