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Issue 3, 2015
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A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates

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Abstract

A generalised, simple and efficient synthesis of N-acetyl-5-bromo-4-chloroindoxyl and related analogues required for the synthesis of indigogenic substrates to probe for biological activities is reported. The method is both synthetically and operationally simple and represents a significant improvement on existing methods.

Graphical abstract: A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates

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Publication details

The article was received on 22 Oct 2014, accepted on 10 Nov 2014 and first published on 10 Nov 2014


Article type: Paper
DOI: 10.1039/C4OB02248C
Citation: Org. Biomol. Chem., 2015,13, 905-908

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    A simple and robust preparation of N-acetylindoxyls: precursors for indigogenic substrates

    M. N. Gandy, L. T. Byrne and K. A. Stubbs, Org. Biomol. Chem., 2015, 13, 905
    DOI: 10.1039/C4OB02248C

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