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Issue 3, 2015
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A phthalimidation protocol that follows protein defined parameters

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Abstract

This work outlines the first phthalimidation protocol suitable for protein labeling and performed in aqueous media at room temperature and neutral pH with no catalyst or co-reagent required. The methodology is suitable for a range of amines and its efficiency was determined with chemoselective and site-selective protein labeling.

Graphical abstract: A phthalimidation protocol that follows protein defined parameters

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Article information


Submitted
28 Oct 2014
Accepted
14 Nov 2014
First published
14 Nov 2014

Chem. Commun., 2015,51, 473-476
Article type
Communication
Author version available

A phthalimidation protocol that follows protein defined parameters

R. Singudas, S. R. Adusumalli, P. N. Joshi and V. Rai, Chem. Commun., 2015, 51, 473
DOI: 10.1039/C4CC08503E

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