One-pot synthesis of super-bright fluorescent nanogel contrast agents containing a dithiomaleimide fluorophore†
Fluorescent nanogels with radii ranging from 12–17 nm, high quantum yield, concentration-independent emission, and fluorescent lifetimes of ca. 25 ns have been synthesised in a one-pot process. Solutions demonstrate a concentration independent emission between 0.1–10−3 wt%, allowing for true quantitative imaging where dye emission is a measure of local nanoparticle concentration.
- This article is part of the themed collection: Celebrating the 2016 RSC Prize and Award Winners