Issue 2, 2016

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

Abstract

Antibiotic resistance is a global health concern meaning there is an urgent need for new treatments and diagnostics. Here glycosylated surfaces are used to profile the binding patterns of a range of Gram-negative, Gram-positive and mycobacteria. This enables the creation of ‘barcodes’ to enable identification and discrimination between the strains, which could not be achieved by single-point glycan binding and offers a new concept in bacteria detection.

Graphical abstract: Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

Supplementary files

Article information

Article type
Communication
Submitted
26 Oct 2015
Accepted
30 Nov 2015
First published
01 Dec 2015
This article is Open Access
Creative Commons BY license

Mol. BioSyst., 2016,12, 341-344

Author version available

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

L. Otten, E. Fullam and M. I. Gibson, Mol. BioSyst., 2016, 12, 341 DOI: 10.1039/C5MB00720H

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