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Issue 13, 2015
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Principles of transverse flow fractionation of microparticles in superhydrophobic channels

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Abstract

We propose a concept of fractionation of micron-sized particles in a microfluidic device with a bottom wall decorated by superhydrophobic stripes. The stripes are oriented at an angle α to the direction of a driving force, G, which generally includes an applied pressure gradient and gravity. Separation relies on the initial sedimentation of particles under gravity in the main forward flow, and their subsequent lateral deflection near a superhydrophobic wall due to generation of a secondary flow transverse to G. We provide some theoretical arguments allowing us to quantify the transverse displacement of particles in the microfluidic channel, and confirm the validity of theoretical predictions in test experiments with monodisperse fractions of microparticles. Our results can guide the design of superhydrophobic microfluidic devices for efficient sorting of microparticles with a relatively small difference in size and density.

Graphical abstract: Principles of transverse flow fractionation of microparticles in superhydrophobic channels

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Article information


Submitted
15 Mar 2015
Accepted
13 May 2015
First published
13 May 2015

Lab Chip, 2015,15, 2835-2841
Article type
Paper
Author version available

Principles of transverse flow fractionation of microparticles in superhydrophobic channels

E. S. Asmolov, A. L. Dubov, T. V. Nizkaya, A. J. C. Kuehne and O. I. Vinogradova, Lab Chip, 2015, 15, 2835
DOI: 10.1039/C5LC00310E

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