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Issue 4, 2015
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Characterization of syringe-pump-driven induced pressure fluctuations in elastic microchannels

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Abstract

We study pressure and flow-rate fluctuations in microchannels, where the flow rate is supplied by a syringe pump. We demonstrate that the pressure fluctuations are induced by the flow-rate fluctuations coming from mechanical oscillations of the pump motor. Also, we provide a mathematical model of the effect of the frequency of the pump on the normalized amplitude of pressure fluctuations and introduce a dimensionless parameter incorporating pump frequency, channel geometry and mechanical properties that can be used to predict the performance of different microfluidic device configurations. The normalized amplitude of pressure fluctuations decreases as the frequency of the pump increases and the elasticity of the channel material decreases. The mathematical model is verified experimentally over a range of typical operating conditions and possible applications are discussed.

Graphical abstract: Characterization of syringe-pump-driven induced pressure fluctuations in elastic microchannels

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Article information


Submitted
12 Nov 2014
Accepted
17 Dec 2014
First published
24 Dec 2014

Lab Chip, 2015,15, 1110-1115
Article type
Paper
Author version available

Characterization of syringe-pump-driven induced pressure fluctuations in elastic microchannels

W. Zeng, I. Jacobi, D. J. Beck, S. Li and H. A. Stone, Lab Chip, 2015, 15, 1110
DOI: 10.1039/C4LC01347F

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