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Issue 2, 2015
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Development of GSK's acid and base selection guides

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Abstract

Further to the introduction of solvent and reagent guides at GSK, the reagent guide methodology has been adapted to score common acids and bases for use in situations where the chemistry is tolerant of a number of options. The pKa of each acid and base, and information as to whether they are generally recognised as safe are included to enhance the utility of such guides.

Graphical abstract: Development of GSK's acid and base selection guides

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The article was received on 01 Aug 2014, accepted on 24 Sep 2014 and first published on 25 Sep 2014


Article type: Paper
DOI: 10.1039/C4GC01481B
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Green Chem., 2015,17, 945-949

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    Development of GSK's acid and base selection guides

    R. K. Henderson, A. P. Hill, A. M. Redman and H. F. Sneddon, Green Chem., 2015, 17, 945
    DOI: 10.1039/C4GC01481B

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