Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 21st October 2020 from 07:00 AM to 07:00 PM (BST).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 27, 2015
Previous Article Next Article

Exploring the decomposition pathways of iron asymmetric transfer hydrogenation catalysts

Author affiliations

Abstract

Our group has developed a series of iron-based asymmetric transfer hydrogenation (ATH) catalysts for the reduction of polar double bonds. The activation of the precatalysts as well as the catalytic mechanism have been thoroughly investigated, but the decomposition pathways of these systems are poorly understood. Herein, we report a study of the deactivation pathways for an iron ATH catalyst under catalytically relevant conditions. The decomposition pathways were examined using experimental techniques and density functional theory (DFT) calculations. The major decomposition products that formed, Fe(CO)((Et)2PCH2CH2CHCHNCH2CH2P(Et)2) (3a) and Fe(CO)((Et)2PCH2CH2C(Ph)C(Ph)NCH2CH2P(Et)2) (3b), had two amido donors as well as a C[double bond, length as m-dash]C bond on the diamine backbone of the tetradentate ligand. These species were identified by NMR studies and one was isolated as a bimetallic complex with Ru(II)Cp*. Two minor iron hydride species also formed concurrently with 3a, as determined by NMR studies, one of which was isolated and contained a fully saturated ligand as well as a hydride ligand. None of the compounds that were isolated were found to be active ATH catalysts.

Graphical abstract: Exploring the decomposition pathways of iron asymmetric transfer hydrogenation catalysts

Back to tab navigation

Supplementary files

Article information


Submitted
12 Sep 2014
Accepted
23 Oct 2014
First published
27 Oct 2014

Dalton Trans., 2015,44, 12119-12127
Article type
Paper
Author version available

Exploring the decomposition pathways of iron asymmetric transfer hydrogenation catalysts

P. O. Lagaditis, P. E. Sues, A. J. Lough and R. H. Morris, Dalton Trans., 2015, 44, 12119
DOI: 10.1039/C4DT02799J

Social activity

Search articles by author

Spotlight

Advertisements