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Issue 13, 2015
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Optical probes for the detection of protons, and alkali and alkaline earth metal cations

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Abstract

Luminescent sensors and switches continue to play a key role in shaping our understanding of key biochemical processes, assist in the diagnosis of disease and contribute to the design of new drugs and therapies. Similarly, their contribution to the environment cannot be understated as they offer a portable means to undertake field testing for hazardous chemicals and pollutants such as heavy metals. From a physiological perspective, the Group I and II metal ions are among the most important in the periodic table with blood plasma levels of H+, Na+ and Ca2+ being indicators of several possible disease states. In this review, we examine the progress that has been made in the development of luminescent probes for Group I and Group II ions as well as protons. The potential applications of these probes and the mechanism involved in controlling their luminescent response upon analyte binding will also be discussed.

Graphical abstract: Optical probes for the detection of protons, and alkali and alkaline earth metal cations

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Publication details

The article was received on 03 Nov 2014 and first published on 06 Mar 2015


Article type: Review Article
DOI: 10.1039/C4CS00365A
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Chem. Soc. Rev., 2015,44, 4415-4432

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    Optical probes for the detection of protons, and alkali and alkaline earth metal cations

    G. R. C. Hamilton, S. K. Sahoo, S. Kamila, N. Singh, N. Kaur, B. W. Hyland and J. F. Callan, Chem. Soc. Rev., 2015, 44, 4415
    DOI: 10.1039/C4CS00365A

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