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Issue 12, 2015
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Dendritic nanocarriers based on hyperbranched polymers

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Abstract

Hyperbranched polymers are obtained through one-step polymerization reactions and exhibit properties that are very similar to those of perfect dendrimer analogues. Therefore, hyperbranched polymers are a suitable alternative for perfect dendrimers as building blocks for dendritic nanocarrier systems. With regard to using soluble hyperbranched polymers as carrier systems, their flexible chains are a major benefit as they can adopt and compartment guest molecules. Upon encapsulation, the properties of the host decides the fate of the guest, e.g., solubility, but the host can also shield a guest from the environment and protect it, e.g., from degradation and deactivation. With regard to the advantages of using hyperbranched polymers as nanocarrier systems and their scalable synthesis, we will discuss different types of hyperbranched polymers and their application as nanocarrier systems for drugs, dyes, and other guest molecules.

Graphical abstract: Dendritic nanocarriers based on hyperbranched polymers

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Article information


Submitted
06 Oct 2014
First published
18 May 2015

This article is Open Access

Chem. Soc. Rev., 2015,44, 4145-4164
Article type
Review Article
Author version available

Dendritic nanocarriers based on hyperbranched polymers

I. N. Kurniasih, J. Keilitz and R. Haag, Chem. Soc. Rev., 2015, 44, 4145
DOI: 10.1039/C4CS00333K

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