Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors†
Whereas spatial organisation of function is ubiquitous in biology, it has been lacking in artificial cells. We rectify this by using multi-compartment vesicles as chassis for artificial cells, allowing distinct biological processes to be isolated in space. This is demonstrated by in vitro synthesis of two proteins in predefined vesicle regions.
- This article is part of the themed collection: Chemical compartmentalisation by membranes: from biological mechanism to biomimetic applications