Issue 33, 2015
From the journal:

Physical Chemistry Chemical Physics

Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

Natalie L. Garrett,ab   Ryo Sekine,ac   Matthew W. A. Dixon,d   Leann Tilley,d   Keith R. Bamberye  and  Bayden R. Wood*a  

* Corresponding authors

a Centre for Biospectroscopy, School of Chemistry, Monash University, Victoria, Australia
E-mail: Bayden.wood@monash.edu

b School of Physics, University of Exeter, Stocker Road, Exeter, Devon, UK

c Centre for Environmental Risk Assessment and Remediation, University of South Australia, Mawson Lakes, South Australia 5095, Australia

d Department of Biochemistry and Molecular Biology, Bio21 Institute, The University of Melbourne, Victoria 3010, Australia

e Australian Synchrotron, 800 Blackburn Rd Clayton, Victoria 3168, Australia

Abstract

Surface enhanced Raman scattering (SERS) is a powerful tool with great potential to provide improved bio-sensing capabilities. The current ‘gold-standard’ method for diagnosis of malaria involves visual inspection of blood smears using light microscopy, which is time consuming and can prevent early diagnosis of the disease. We present a novel surface-enhanced Raman spectroscopy substrate based on gold-coated butterfly wings, which enabled detection of malarial hemozoin pigment within lysed blood samples containing 0.005% and 0.0005% infected red blood cells.

Graphical abstract: Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

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Article information

DOI
https://doi.org/10.1039/C4CP04930F
Article type
Paper
Submitted
28 Oct 2014
Accepted
03 Dec 2014
First published
03 Dec 2014

Phys. Chem. Chem. Phys., 2015,17, 21164-21168

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Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

N. L. Garrett, R. Sekine, M. W. A. Dixon, L. Tilley, K. R. Bambery and B. R. Wood, Phys. Chem. Chem. Phys., 2015, 17, 21164 DOI: 10.1039/C4CP04930F

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