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Issue 33, 2015
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Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

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Abstract

Surface enhanced Raman scattering (SERS) is a powerful tool with great potential to provide improved bio-sensing capabilities. The current ‘gold-standard’ method for diagnosis of malaria involves visual inspection of blood smears using light microscopy, which is time consuming and can prevent early diagnosis of the disease. We present a novel surface-enhanced Raman spectroscopy substrate based on gold-coated butterfly wings, which enabled detection of malarial hemozoin pigment within lysed blood samples containing 0.005% and 0.0005% infected red blood cells.

Graphical abstract: Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

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Publication details

The article was received on 28 Oct 2014, accepted on 03 Dec 2014 and first published on 03 Dec 2014


Article type: Paper
DOI: 10.1039/C4CP04930F
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Phys. Chem. Chem. Phys., 2015,17, 21164-21168

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    Bio-sensing with butterfly wings: naturally occurring nano-structures for SERS-based malaria parasite detection

    N. L. Garrett, R. Sekine, M. W. A. Dixon, L. Tilley, K. R. Bambery and B. R. Wood, Phys. Chem. Chem. Phys., 2015, 17, 21164
    DOI: 10.1039/C4CP04930F

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