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Issue 100, 2015

Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

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Abstract

The amphiphilic polyene amphotericin B, a powerful treatment for systemic fungal infections, is shown to exhibit a critical aggregation concentration, and to form giant helically-twisted nanostructures via self-assembly in basic aqueous solution.

Graphical abstract: Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

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Supplementary files

Article information


Submitted
02 Oct 2015
Accepted
20 Oct 2015
First published
20 Oct 2015

This article is Open Access

Chem. Commun., 2015,51, 17680-17683
Article type
Communication

Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

I. W. Hamley, S. Kirkham, R. M. Kowalczyk, V. Castelletto, M. Reza and J. Ruokolainen, Chem. Commun., 2015, 51, 17680 DOI: 10.1039/C5CC08224B

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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