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Issue 98, 2015
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Dynamic flow synthesis of porous organic cages

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The dynamic covalent synthesis of two imine-based porous organic cages was successfully transferred from batch to continuous flow. The same flow reactor was then used to scramble the constituents of these two cages in differing ratios to form cage mixtures. Preparative HPLC purification of one of these mixtures allowed rapid access to a desymmetrised cage molecule.

Graphical abstract: Dynamic flow synthesis of porous organic cages

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The article was received on 04 Sep 2015, accepted on 06 Oct 2015 and first published on 07 Oct 2015

Article type: Communication
DOI: 10.1039/C5CC07447A
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Chem. Commun., 2015,51, 17390-17393

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    Dynamic flow synthesis of porous organic cages

    M. E. Briggs, A. G. Slater, N. Lunt, S. Jiang, M. A. Little, R. L. Greenaway, T. Hasell, C. Battilocchio, S. V. Ley and A. I. Cooper, Chem. Commun., 2015, 51, 17390
    DOI: 10.1039/C5CC07447A

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