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Issue 98, 2015
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Dynamic flow synthesis of porous organic cages

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The dynamic covalent synthesis of two imine-based porous organic cages was successfully transferred from batch to continuous flow. The same flow reactor was then used to scramble the constituents of these two cages in differing ratios to form cage mixtures. Preparative HPLC purification of one of these mixtures allowed rapid access to a desymmetrised cage molecule.

Graphical abstract: Dynamic flow synthesis of porous organic cages

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04 Sep 2015
06 Oct 2015
First published
07 Oct 2015

Chem. Commun., 2015,51, 17390-17393
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Author version available

Dynamic flow synthesis of porous organic cages

M. E. Briggs, A. G. Slater, N. Lunt, S. Jiang, M. A. Little, R. L. Greenaway, T. Hasell, C. Battilocchio, S. V. Ley and A. I. Cooper, Chem. Commun., 2015, 51, 17390
DOI: 10.1039/C5CC07447A

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