Issue 87, 2015

MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

Abstract

We report the synthesis of MOF@lipid nanoparticles as a versatile and powerful novel class of nanocarriers based on metal–organic frameworks (MOFs). We show that the MOF@lipid system can effectively store dye molecules inside the porous scaffold of the MOF while the lipid bilayer prevents their premature release. Efficient uptake of the MOF@lipid nanoparticles by cancer cells makes these nanocarriers promising for drug delivery and diagnostic purposes.

Graphical abstract: MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

Supplementary files

Article information

Article type
Communication
Submitted
12 Aug 2015
Accepted
04 Sep 2015
First published
11 Sep 2015
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2015,51, 15752-15755

MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

S. Wuttke, S. Braig, T. Preiß, A. Zimpel, J. Sicklinger, C. Bellomo, J. O. Rädler, A. M. Vollmar and T. Bein, Chem. Commun., 2015, 51, 15752 DOI: 10.1039/C5CC06767G

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