Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 81, 2015
Previous Article Next Article

Copper-catalyzed oxidative decarboxylative C–H arylation of benzoxazoles with 2-nitrobenzoic acids

Author affiliations

Abstract

A copper-catalyzed oxidative decarboxylative coupling of benzoxazoles with 2-nitrobenzoic acids was developed. This methodology favors electron-rich benzoxazoles and electron-deficient benzoic acids and enables the preparation of a variety of arylated benzoxazoles in good yields. The trends in product yields suggest a delicate balance between the decarboxylation and C–H arylation steps.

Graphical abstract: Copper-catalyzed oxidative decarboxylative C–H arylation of benzoxazoles with 2-nitrobenzoic acids

Back to tab navigation

Supplementary files

Publication details

The article was received on 07 Aug 2015, accepted on 21 Aug 2015 and first published on 21 Aug 2015


Article type: Communication
DOI: 10.1039/C5CC06645J
Author version
available:
Download author version (PDF)
Citation: Chem. Commun., 2015,51, 15059-15062

  •   Request permissions

    Copper-catalyzed oxidative decarboxylative C–H arylation of benzoxazoles with 2-nitrobenzoic acids

    L. Chen, L. Ju, K. A. Bustin and J. M. Hoover, Chem. Commun., 2015, 51, 15059
    DOI: 10.1039/C5CC06645J

Search articles by author

Spotlight

Advertisements