Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 75, 2015
Previous Article Next Article

Continuous flow synthesis of a carbon-based molecular cage macrocycle via a three-fold homocoupling reaction

Author affiliations

Abstract

The facile synthesis of the cage molecule (C110H56Br2) via a remarkable three-fold homo-coupling macrocyclization reaction using continuous flow methodology is reported. Synthesis via continuous flow chemistry improves the residence time, safety, and environmental profile of this synthetically challenging reaction. Further, the new cage possesses halogen atoms at its apex that serve to expand the potential reaction space of these intrinsically porous, all carbon–carbon bonded molecular cage molecules.

Graphical abstract: Continuous flow synthesis of a carbon-based molecular cage macrocycle via a three-fold homocoupling reaction

Back to tab navigation

Supplementary files

Article information


Submitted
24 Jun 2015
Accepted
01 Aug 2015
First published
03 Aug 2015

Chem. Commun., 2015,51, 14231-14234
Article type
Communication

Continuous flow synthesis of a carbon-based molecular cage macrocycle via a three-fold homocoupling reaction

M. Kitchin, K. Konstas, C. J. Sumby, M. L. Czyz, P. Valente, M. R. Hill, A. Polyzos and C. J. Doonan, Chem. Commun., 2015, 51, 14231
DOI: 10.1039/C5CC05181A

Social activity

Search articles by author

Spotlight

Advertisements