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Issue 61, 2015
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PLA2-responsive and SPIO-loaded phospholipid micelles

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Abstract

PLA2-responsive and superparamagnetic iron oxide (SPIO) nanoparticle-loaded phospholipid micelles were developed. The release of a phospholipid-conjugated dye from these micelles was triggered due to phospholipid degradation by phospholipase A2. The high relaxivity of the encapsulated SPIO could enable non-invasive magnetic resonance imaging.

Graphical abstract: PLA2-responsive and SPIO-loaded phospholipid micelles

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Article information


Submitted
02 Jun 2015
Accepted
24 Jun 2015
First published
24 Jun 2015

Chem. Commun., 2015,51, 12313-12315
Article type
Communication
Author version available

PLA2-responsive and SPIO-loaded phospholipid micelles

Q. Gao, L. Yan, M. Chiorazzo, E. James Delikatny, A. Tsourkas and Z. Cheng, Chem. Commun., 2015, 51, 12313
DOI: 10.1039/C5CC04540A

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