We report a two-photon fluorescent probe which shows a strong two photon excited fluorescence enhancement in response to Zn2+, easy loading into the cells, Golgi-localizing ability, low cytotoxicity, and high photostability. Two-photon microscopy imaging revealed that this probe allows for real-time monitoring of the changes in Golgi Zn2+ as well as their 3D distributions in live cells and tissues.
H. Singh, H. W. Lee, C. H. Heo, J. W. Byun, A. R. Sarkar and H. M. Kim, Chem. Commun., 2015, 51, 12099 DOI: 10.1039/C5CC03884G
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