Issue 58, 2015
From the journal:

Chemical Communications

Integration of DNA bio-gates and duplex-specific nuclease signal amplification: towards electrochemiluminescence detection of survivin mRNA†

Jing Wang,ab   Xiang-Ling Li,a   Jia-Dong Zhang,a   Nan Hao,a   Jing-Juan Xu*a  and  Hong-Yuan Chen*a  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, Jiangsu, P. R. China
E-mail: xujj@nju.edu.cn, hychen@nju.edu.cn
Fax: +86-25-83597294
Tel: +86-25-83597294

b Department of Analytical Chemistry, School of Science, China Pharmaceutical University, Nanjing 210009, China

Abstract

Using the DNA bio-gate and duplex-specific nuclease assisted target recycling, a facile electrochemiluminescence assay was developed for the sensitive detection of survivin mRNA.

Graphical abstract: Integration of DNA bio-gates and duplex-specific nuclease signal amplification: towards electrochemiluminescence detection of survivin mRNA

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Article information

DOI
https://doi.org/10.1039/C5CC03693C
Article type
Communication
Submitted
04 May 2015
Accepted
09 Jun 2015
First published
09 Jun 2015

Chem. Commun., 2015,51, 11673-11676

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Integration of DNA bio-gates and duplex-specific nuclease signal amplification: towards electrochemiluminescence detection of survivin mRNA

J. Wang, X. Li, J. Zhang, N. Hao, J. Xu and H. Chen, Chem. Commun., 2015, 51, 11673 DOI: 10.1039/C5CC03693C

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