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Issue 52, 2015
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A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

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Abstract

Understanding the role of oxidative stress in disease requires real time monitoring of redox status within a cell. We report a FRET-based, ratiometric redox probe which can be applied to monitor cellular oxidative capacity using three different modalities – confocal microscopy, fluorescence lifetime imaging and flow cytometry.

Graphical abstract: A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

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Publication details

The article was received on 23 Apr 2015, accepted on 29 May 2015 and first published on 03 Jun 2015


Article type: Communication
DOI: 10.1039/C5CC03394B
Citation: Chem. Commun., 2015,51, 10510-10513
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    A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

    A. Kaur, M. A. Haghighatbin, C. F. Hogan and E. J. New, Chem. Commun., 2015, 51, 10510
    DOI: 10.1039/C5CC03394B

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