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Issue 52, 2015
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A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

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Abstract

Understanding the role of oxidative stress in disease requires real time monitoring of redox status within a cell. We report a FRET-based, ratiometric redox probe which can be applied to monitor cellular oxidative capacity using three different modalities – confocal microscopy, fluorescence lifetime imaging and flow cytometry.

Graphical abstract: A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

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Supplementary files

Article information


Submitted
23 Apr 2015
Accepted
29 May 2015
First published
03 Jun 2015

Chem. Commun., 2015,51, 10510-10513
Article type
Communication

A FRET-based ratiometric redox probe for detecting oxidative stress by confocal microscopy, FLIM and flow cytometry

A. Kaur, M. A. Haghighatbin, C. F. Hogan and E. J. New, Chem. Commun., 2015, 51, 10510
DOI: 10.1039/C5CC03394B

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