Issue 57, 2015
From the journal:

Chemical Communications

Hybridization chain reaction engineered dsDNA for Cu metallization: an enzyme-free platform for amplified detection of cancer cells and microRNAs†

Yan Zhang,ab   Zhaowei Chen,ab   Yu Tao,ab   Zhenzhen Wang,ab   Jinsong Ren*a  and  Xiaogang Qu*a  

* Corresponding authors

a Laboratory of Chemical Biology, State Key laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China
E-mail: jren@ciac.ac.cn, xqu@ciac.ac.cn

b University of the Chinese Academy of Sciences, Beijing, China

Abstract

A novel enzyme-free platform for amplified detection of cancer cells and miRNAs was constructed with high sensitivity by fluorescent Cu metallization on HCR engineered dsDNA templates.

Graphical abstract: Hybridization chain reaction engineered dsDNA for Cu metallization: an enzyme-free platform for amplified detection of cancer cells and microRNAs

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Article information

DOI
https://doi.org/10.1039/C5CC03144C
Article type
Communication
Submitted
16 Apr 2015
Accepted
03 Jun 2015
First published
04 Jun 2015

Chem. Commun., 2015,51, 11496-11499

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Hybridization chain reaction engineered dsDNA for Cu metallization: an enzyme-free platform for amplified detection of cancer cells and microRNAs

Y. Zhang, Z. Chen, Y. Tao, Z. Wang, J. Ren and X. Qu, Chem. Commun., 2015, 51, 11496 DOI: 10.1039/C5CC03144C

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