A novel thermo-sensitive micelle contrast agent and its enhancement of MRI contrast with temperature are reported. The morphology changes sharply near 37 °C, resulting in a significant amplification of the CEST signal. This enables detection of small changes in body temperature.
X. Zhu, S. Chen, Q. Luo, C. Ye, M. Liu and X. Zhou, Chem. Commun., 2015, 51, 9085 DOI: 10.1039/C5CC02587G
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