The 13C amide I band is still sensitive to conformation change when the regular amide I band cannot be distinguished at the typical position in H2O†
Abstract
The attenuated total reflection technique was utilized to obtain FTIR spectra of 13C-labeled peptides with a sequence of (AAAAK)4AAAAY in H2O. The regular amide I band was not at the typical position as reported in globular proteins, whereas the 13C amide I band was still sensitive to conformation change.