Issue 39, 2015
From the journal:

Chemical Communications

A double-enhanced strip biosensor for the rapid and ultrasensitive detection of protein biomarkers†

Chunyan Qin,a   Wei Wen,a   Xiuhua Zhang,a   Haoshuang Gua  and  Shengfu Wang*a  

* Corresponding authors

a Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P. R. China
E-mail: wangsf@hubu.edu.cn

Abstract

Combining the specific molecular recognition reaction between biotin and streptavidin with a dual-class signal amplification system, containing the unique optical properties of gold nanoparticles and the catalytic reaction of horseradish peroxidase, a double-enhanced strip biosensor was designed for the first time for a visual and rapid detection of protein biomarkers with good accuracy, especially for CEA with a detection limit of 2.9 fg mL−1.

Graphical abstract: A double-enhanced strip biosensor for the rapid and ultrasensitive detection of protein biomarkers

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Article information

DOI
https://doi.org/10.1039/C5CC01975C
Article type
Communication
Submitted
10 Mar 2015
Accepted
07 Apr 2015
First published
07 Apr 2015

Chem. Commun., 2015,51, 8273-8275

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A double-enhanced strip biosensor for the rapid and ultrasensitive detection of protein biomarkers

C. Qin, W. Wen, X. Zhang, H. Gu and S. Wang, Chem. Commun., 2015, 51, 8273 DOI: 10.1039/C5CC01975C

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