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Issue 30, 2015
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An aryl-thioether substituted nitrobenzothiadiazole probe for the selective detection of cysteine and homocysteine

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Abstract

An aryl-thioether substituted nitrobenzothiadiazole probe was synthesized and employed to detect cysteine and homocysteine selectively in living cells. Interestingly, both cysteine (Cys) and homocysteine (Hcy) promote an enhancement of the fluorescence intensity of the probe at pH 7.4 while only Cys gives rise to this enhancement under weakly acidic conditions (pH 6.0).

Graphical abstract: An aryl-thioether substituted nitrobenzothiadiazole probe for the selective detection of cysteine and homocysteine

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Publication details

The article was received on 05 Feb 2015, accepted on 26 Feb 2015 and first published on 27 Feb 2015


Article type: Communication
DOI: 10.1039/C5CC01071C
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Chem. Commun., 2015,51, 6518-6520

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    An aryl-thioether substituted nitrobenzothiadiazole probe for the selective detection of cysteine and homocysteine

    D. Lee, G. Kim, J. Yin and J. Yoon, Chem. Commun., 2015, 51, 6518
    DOI: 10.1039/C5CC01071C

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