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Issue 27, 2015
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Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts

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Abstract

Azetidine and oxetane sulfinate salts are easily prepared from commercially available 3-iodoheterocycle precursors in a three-step sequence. They undergo smooth coupling reactions thereby providing an expedient route for the introduction of these four-membered heterocycles into indoles.

Graphical abstract: Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts

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Article information


Submitted
02 Feb 2015
Accepted
23 Feb 2015
First published
24 Feb 2015

Chem. Commun., 2015,51, 5914-5916
Article type
Communication

Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts

A. M. A. Nassoy, P. Raubo and J. P. A. Harrity, Chem. Commun., 2015, 51, 5914
DOI: 10.1039/C5CC00975H

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