G. Neri, A. Scala, F. Barreca, E. Fazio, P. G. Mineo, A. Mazzaglia, G. Grassi and A. Piperno
Chem. Commun., 2015,51, 4846-4849
DOI:
10.1039/C5CC00518C,
Communication
A reactive azlactone-based graphene nanoplatform was successfully synthesized by the ligation of azido-azlactone with alkyne-terminated graphene via Cu(I)-catalyzed cycloaddition. The reactive azlactone rings, grafted on graphene sheets, were subjected to highly efficient ring-opening reactions with functionalized primary amine derivatives incorporating an aminosilane coupling agent or a biological fragment.