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Issue 27, 2015
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Combining a sensor and a pH-gated nanopore based on an avidin–biotin system

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Abstract

Here we propose a new approach to tailor nanopores, which combines both pH gating and sensing properties. This strategy is based on PEG like-avidin grafting in nanopores designed by atomic layer deposition (ALD). Below pH 5 the nanopore is blocked. We show that the PEG chains are at the origin of these properties.

Graphical abstract: Combining a sensor and a pH-gated nanopore based on an avidin–biotin system

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Supplementary files

Article information


Submitted
17 Dec 2014
Accepted
27 Feb 2015
First published
27 Feb 2015

Chem. Commun., 2015,51, 5994-5997
Article type
Communication
Author version available

Combining a sensor and a pH-gated nanopore based on an avidin–biotin system

M. Lepoitevin, G. Nguyen, M. Bechelany, E. Balanzat, J. Janot and S. Balme, Chem. Commun., 2015, 51, 5994
DOI: 10.1039/C4CC10087E

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