Issue 14, 2015

Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging

Abstract

Herein, we show that a far-red arylidene–squaraine dye is stable against nucleophiles, in contrast to arene–squaraines. Owing to the fluorescence enhancement in apolar media together with high brightness and photostability, this dye was successfully applied to detect the oxytocin G protein-coupled receptor and monitor its internalization in living cells.

Graphical abstract: Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging

Supplementary files

Article information

Article type
Communication
Submitted
14 Nov 2014
Accepted
23 Dec 2014
First published
07 Jan 2015
This article is Open Access
Creative Commons BY license

Chem. Commun., 2015,51, 2960-2963

Author version available

Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging

I. A. Karpenko, A. S. Klymchenko, S. Gioria, R. Kreder, I. Shulov, P. Villa, Y. Mély, M. Hibert and D. Bonnet, Chem. Commun., 2015, 51, 2960 DOI: 10.1039/C4CC09113B

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