An ultrasensitive cytosensor based on DNA-rolling-circle-amplification-directed enzyme-catalyzed polymerization is demonstrated. As a proof of concept, the cytosensor shows excellent sensitivity for MCF-7 cell detection with a lower detection limit of 12 cells per mL.
Q. Sheng, N. Cheng, W. Bai and J. Zheng, Chem. Commun., 2015, 51, 2114 DOI: 10.1039/C4CC08954E
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