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Issue 7, 2015
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Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity

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Abstract

This work demonstrates a design strategy to optimize antimicrobial peptides with an ideal balance of minimal cytotoxicity, enhanced stability, potent cell penetration and effective antimicrobial activity, which hold great promise for the treatment of intracellular microbial infections and potentially systemic anti-infective therapy.

Graphical abstract: Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity

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Publication details

The article was received on 07 Nov 2014, accepted on 26 Nov 2014 and first published on 26 Nov 2014


Article type: Communication
DOI: 10.1039/C4CC08808E
Chem. Commun., 2015,51, 1289-1292

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    Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity

    D. Xu, L. Jiang, A. Singh, D. Dustin, M. Yang, L. Liu, R. Lund, T. J. Sellati and H. Dong, Chem. Commun., 2015, 51, 1289
    DOI: 10.1039/C4CC08808E

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