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Issue 7, 2015
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Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity

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Abstract

This work demonstrates a design strategy to optimize antimicrobial peptides with an ideal balance of minimal cytotoxicity, enhanced stability, potent cell penetration and effective antimicrobial activity, which hold great promise for the treatment of intracellular microbial infections and potentially systemic anti-infective therapy.

Graphical abstract: Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity

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Article information


Submitted
07 Nov 2014
Accepted
26 Nov 2014
First published
26 Nov 2014

Chem. Commun., 2015,51, 1289-1292
Article type
Communication

Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity

D. Xu, L. Jiang, A. Singh, D. Dustin, M. Yang, L. Liu, R. Lund, T. J. Sellati and H. Dong, Chem. Commun., 2015, 51, 1289
DOI: 10.1039/C4CC08808E

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