Determination of receptor specificities for whole influenza viruses using multivalent glycan arrays†
Influenza viruses bind to mucosal glycans to gain entry into a host organism and initiate infection. The target glycans are often displayed in multivalent arrangements on proteins; however, how glycan presentation influences viral specificity is poorly understood. Here, we report a microarray platform approximating native glycan display to facilitate such studies.
- This article is part of the themed collection: 2015 Emerging Investigators