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Issue 29, 2015
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Fluorescent sensing of monofunctional platinum species

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Abstract

We report here FDCPt1, a novel selective fluorescent sensor for monofunctional platinum species. In the presence of such species, FDCPt1 exhibits a 70-fold increase in fluorescence emission, and can be used to monitor the metabolism of Pt(II)-based complexes in colorectal cancer cells. This probe is therefore expected to be valuable in studying changes in Pt coordination and distribution during chemotherapy.

Graphical abstract: Fluorescent sensing of monofunctional platinum species

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Supplementary files

Article information


Submitted
13 Oct 2014
Accepted
04 Mar 2015
First published
11 Mar 2015

This article is Open Access

Chem. Commun., 2015,51, 6312-6314
Article type
Communication

Fluorescent sensing of monofunctional platinum species

C. Shen, B. D. W. Harris, L. J. Dawson, K. A. Charles, T. W. Hambley and E. J. New, Chem. Commun., 2015, 51, 6312
DOI: 10.1039/C4CC08077G

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