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Issue 12, 2015
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The coaction of tonic and phasic dopamine dynamics

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Abstract

Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10−6 cm2 s−1) in the mouse brain.

Graphical abstract: The coaction of tonic and phasic dopamine dynamics

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Article information


Submitted
11 Aug 2014
Accepted
15 Sep 2014
First published
24 Sep 2014

Chem. Commun., 2015,51, 2235-2238
Article type
Communication
Author version available

The coaction of tonic and phasic dopamine dynamics

C. W. Atcherley, K. M. Wood, K. L. Parent, P. Hashemi and M. L. Heien, Chem. Commun., 2015, 51, 2235
DOI: 10.1039/C4CC06165A

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