Jump to main content
Jump to site search

Issue 9, 2015
Previous Article Next Article

Colorimetric detection of bisphenol A using Au–Fe alloy nanoparticle aggregation

Author affiliations

Abstract

A colorimetric assay for bisphenol A (BPA) detection was developed based on Au–Fe alloy nanoparticles. Au–Fe alloy nanoparticles were synthesized and optimized by a hydrothermal method. In the colorimetric assay, horseradish peroxidase was introduced to catalyze BPA polymerization in the presence of hydrogen peroxide, which greatly enhances the sensitivity of the assay. Selectivity is achieved by specific phenol–Fe3+ interactions between BPA and the Au–Fe alloy nanoparticles. The limit of detection of BPA is 0.58 μM (S/D = 3). The ratio of absorption at 620 nm to absorption at 520 nm is linear with the BPA concentration in the range of 1.10 μM (0.25 mg L−1) to 70.1 μM (16 mg L−1). Parallel spiked and real polycarbonate samples were tested using the proposed method, and the obtained recoveries ranged from 95% to 103% for different samples. This level of detection is on par or slightly better than that achieved by HPLC using UV detection, which is routinely employed to detect BPA. Compared with HPLC, the colorimetric assay for BPA detection exhibits higher throughput and lower cost, making it suitable for the extensive screening of BPA in samples.

Graphical abstract: Colorimetric detection of bisphenol A using Au–Fe alloy nanoparticle aggregation

Back to tab navigation

Supplementary files

Article information


Submitted
13 Jan 2015
Accepted
30 Mar 2015
First published
30 Mar 2015

Anal. Methods, 2015,7, 3952-3957
Article type
Paper

Colorimetric detection of bisphenol A using Au–Fe alloy nanoparticle aggregation

X. Liang, H. Wang, H. Wang and G. Pei, Anal. Methods, 2015, 7, 3952
DOI: 10.1039/C5AY00090D

Social activity

Search articles by author

Spotlight

Advertisements