Jump to main content
Jump to site search

Issue 4, 2015
Previous Article Next Article

Chemical identification of cannabinoids in street marijuana samples using electrospray ionization FT-ICR mass spectrometry

Author affiliations

Abstract

The Cannabis sativa L. plant is a species rich in a variety of cannabinoid compounds and Δ9-tetrahydrocannabinol (Δ9-THC) has been reported as a main psychotropic substance. In this study, electrospray ionization (ESI), coupled with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), was used in order to perform a direct and fast analysis of street marijuana samples. ESI(−)-FT-ICR MS detected 21 cannabinoid species in the deprotonated form, [M − H]. Other species were detected in regions of m/z 600–800 and 800–1000, corresponding to dimers and trimers of cannabinoids. In addition, ESI(−) was better able to analyze the chemical profile of terpenophenolic species (CcHhOo) than ESI(+). ESI(+)-FT-ICR MS detected the presence of adulterants such as cocaine, lidocaine, and nicotine. Finally, the sensitivity of fast blue B colorimetric testing was also evaluated and the results were compared to the ESI(−)FT-ICR MS data.

Graphical abstract: Chemical identification of cannabinoids in street marijuana samples using electrospray ionization FT-ICR mass spectrometry

Back to tab navigation

Supplementary files

Publication details

The article was received on 04 Oct 2014, accepted on 26 Dec 2014 and first published on 02 Jan 2015


Article type: Paper
DOI: 10.1039/C4AY02355B
Anal. Methods, 2015,7, 1415-1424

  •   Request permissions

    Chemical identification of cannabinoids in street marijuana samples using electrospray ionization FT-ICR mass spectrometry

    I. R. Nascimento, H. B. Costa, L. M. Souza, L. C. Soprani, B. B. Merlo and W. Romão, Anal. Methods, 2015, 7, 1415
    DOI: 10.1039/C4AY02355B

Search articles by author

Spotlight

Advertisements