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Issue 13, 2015
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Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI)

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Abstract

The ever increasing numbers and users of designer drugs means that analytical techniques have to evolve constantly to facilitate their identification and detection. We report that surface enhanced Raman scattering (SERS) offers a relatively fast and inexpensive method for the detection of MDAI at low concentrations. Careful optimisation of the silver sol, and salt concentrations was undertaken to ensure the SERS analysis was both reproducible and sensitive. The optimised system demonstrated acceptable peak variations of less than 15% RSD and resulted in a detection limit of just 8 ppm (5.4 × 10−5 M).

Graphical abstract: Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI)

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Article information


Submitted
25 Mar 2015
Accepted
05 May 2015
First published
05 May 2015

Analyst, 2015,140, 4399-4406
Article type
Paper
Author version available

Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI)

S. Mabbott, O. Alharbi, K. Groves and R. Goodacre, Analyst, 2015, 140, 4399
DOI: 10.1039/C5AN00591D

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