Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 10, 2015
Previous Article Next Article

Applications of tunable resistive pulse sensing

Author affiliations

Abstract

Tunable resistive pulse sensing (TRPS) is an experimental technique that has been used to study and characterise colloidal particles ranging from approximately 50 nm in diameter up to the size of cells. The primary aim of this Review is to provide a guide to the characteristics and roles of TRPS in recent applied research. Relevant studies reflect both the maturation of the technique and the growing importance of submicron colloids in fields such as nanomedicine and biotechnology. TRPS analysis of extracellular vesicles is expanding particularly swiftly, while TRPS studies also extend to on-bead assays using DNA and aptamers, drug delivery particles, viruses and bacteria, food and beverages, and superparamagnetic beads. General protocols for TRPS measurement of particle size, concentration and charge have been developed, and a summary of TRPS technology and associated analysis techniques is included in this Review.

Graphical abstract: Applications of tunable resistive pulse sensing

Back to tab navigation

Supplementary files

Article information


Submitted
11 Dec 2014
Accepted
18 Feb 2015
First published
18 Feb 2015

Analyst, 2015,140, 3318-3334
Article type
Tutorial Review
Author version available

Applications of tunable resistive pulse sensing

E. Weatherall and G. R. Willmott, Analyst, 2015, 140, 3318
DOI: 10.1039/C4AN02270J

Social activity

Search articles by author

Spotlight

Advertisements