Issue 8, 2015

Near-infrared excited ultraviolet emitting upconverting phosphors as an internal light source in dry chemistry test strips for glucose sensing

Abstract

Upconverting phosphors are inorganic crystals with interesting optical properties, including the ability to convert infrared radiation to emission at shorter wavelengths. In this paper we present the utilization of nanosized β-NaYF4:Yb3+,Tm3+, synthesized in the presence of K+, emitting at 365 nm under 980 nm excitation as an internal light source in glucose sensing dry chemistry test strips. The feasibility of the nanoparticles as an internal UV light source was compared to the use of an external broadband lamp. The results obtained from glucose measurements using UCNPs were in agreement with the traditional method based on measuring reflectance using an external UV light source. In addition the multiple emission peaks of UCNPs offered the possibility of using them as a control signal to account for various sources of error arising in the assay. The high penetration depth of the NIR-excitation made it also possible to excite the UCNPs through a layer of whole blood, giving more freedom to the design of the optical setup.

Graphical abstract: Near-infrared excited ultraviolet emitting upconverting phosphors as an internal light source in dry chemistry test strips for glucose sensing

Supplementary files

Article information

Article type
Paper
Submitted
04 Nov 2014
Accepted
13 Jan 2015
First published
13 Jan 2015

Analyst, 2015,140, 2638-2643

Author version available

Near-infrared excited ultraviolet emitting upconverting phosphors as an internal light source in dry chemistry test strips for glucose sensing

T. Valta, V. Kale, T. Soukka and C. Horn, Analyst, 2015, 140, 2638 DOI: 10.1039/C4AN02028F

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