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Issue 17, 2015
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Unusual self-assembly of a hydrophilic β-cyclodextrin inclusion complex into vesicles capable of drug encapsulation and release

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Abstract

Formation of a hydrophilic β-cyclodextrin bis-inclusion complex and its self-assembly into supramolecular vesicles are described. The vesicles can be loaded with the anti-cancer drug doxorubicin and the loaded drug can be released upon addition of a competitive inclusion binder such as adamantane carboxylate.

Graphical abstract: Unusual self-assembly of a hydrophilic β-cyclodextrin inclusion complex into vesicles capable of drug encapsulation and release

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Supplementary files

Article information


Submitted
22 Dec 2014
Accepted
28 Mar 2015
First published
31 Mar 2015

J. Mater. Chem. B, 2015,3, 3425-3428
Article type
Communication
Author version available

Unusual self-assembly of a hydrophilic β-cyclodextrin inclusion complex into vesicles capable of drug encapsulation and release

N. Nayak and K. R. Gopidas, J. Mater. Chem. B, 2015, 3, 3425
DOI: 10.1039/C4TB02114B

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