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Issue 15, 2015
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In vivo multi-photon luminescence imaging of cerebral vasculature and blood–brain barrier integrity using gold nanoparticles

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Abstract

We report that time-dependent morphological changes of cortical vasculature, which would be associated with blood–brain barrier disruption, can be clearly visualized with high spatial resolution in a stroke mouse model using the multi-photon luminescence of long-circulating gold nanoparticles.

Graphical abstract: In vivo multi-photon luminescence imaging of cerebral vasculature and blood–brain barrier integrity using gold nanoparticles

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Supplementary files

Article information


Submitted
23 Oct 2014
Accepted
05 Mar 2015
First published
09 Mar 2015

J. Mater. Chem. B, 2015,3, 2935-2938
Article type
Communication

In vivo multi-photon luminescence imaging of cerebral vasculature and blood–brain barrier integrity using gold nanoparticles

H. Yoon, E. Lee, M. Kang, Y. Jeong and J. Park, J. Mater. Chem. B, 2015, 3, 2935 DOI: 10.1039/C4TB01759E

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