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Issue 102, 2015
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One-step synthesis of fluorescent silicon quantum dots (Si-QDs) and their application for cell imaging

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Abstract

Novel fluorescent silicon quantum dots (Si-QDs) were synthesized by a one-step hydrothermal procedure using (3-aminopropyl)trimethoxysilane (APTES) as a silicon source and sodium ascorbate (SA) as a reducing agent. This synthetic strategy is straightforward, efficacious and low-cost. The as-synthesized Si-QDs featured narrow size distribution, intense purple-blue fluorescence with a photoluminescence quantum yield (PL QY) of 21%, complete water solubility, and favorable biocompatibility. Moreover, the resultant Si-QDs present robust stability in different circumstances, such as for long-term storage in air, in a wide pH range of 2–12 and under continuous UV irradiation, and they also do not respond to some metal ions. Their superior stability and safety render Si-QDs applicable as fluorescent probes in biomedical applications. The use of Si-QDs as an optical probe is illustrated by fluorescent imaging of IE8 cells.

Graphical abstract: One-step synthesis of fluorescent silicon quantum dots (Si-QDs) and their application for cell imaging

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Publication details

The article was received on 09 Jul 2015, accepted on 15 Sep 2015 and first published on 25 Sep 2015


Article type: Paper
DOI: 10.1039/C5RA13119G
RSC Adv., 2015,5, 83581-83587

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    One-step synthesis of fluorescent silicon quantum dots (Si-QDs) and their application for cell imaging

    J. Wu, J. Dai, Y. Shao and Y. Sun, RSC Adv., 2015, 5, 83581
    DOI: 10.1039/C5RA13119G

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