Jump to main content
Jump to site search

Issue 40, 2015
Previous Article Next Article

Pd/mannose promoted tandem cross coupling-nitro reduction: expedient synthesis of aminobiphenyls and aminostilbenes

Author affiliations

Abstract

The dual role of D-mannose as a ligand for Pd catalyzed cross-coupling, and as a hydrogen source for nitro reduction is demonstrated in a modular cross coupling-nitro reduction sequence. The synthetic utility and generality of this green protocol has been illustrated by the synthesis of 20 aminobiphenyl and 10 aminostilbene derivatives in high yields through a one-pot Suzuki coupling-nitro reduction and a Heck coupling-nitro reduction, respectively, starting from halonitroarenes as substrates.

Graphical abstract: Pd/mannose promoted tandem cross coupling-nitro reduction: expedient synthesis of aminobiphenyls and aminostilbenes

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Mar 2015, accepted on 25 Mar 2015 and first published on 25 Mar 2015


Article type: Paper
DOI: 10.1039/C5RA04129E
RSC Adv., 2015,5, 31311-31317

  •   Request permissions

    Pd/mannose promoted tandem cross coupling-nitro reduction: expedient synthesis of aminobiphenyls and aminostilbenes

    S. Rohilla, P. Pant and N. Jain, RSC Adv., 2015, 5, 31311
    DOI: 10.1039/C5RA04129E

Search articles by author

Spotlight

Advertisements