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Issue 13, 2015
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Metal-free synthesis of imidazopyridine from nitroalkene and 2-aminopyridine in the presence of a catalytic amount of iodine and aqueous hydrogen peroxide

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Abstract

We have developed a metal-free synthetic method for 3-nitroimidazo[1,2-a]pyridines from nitroalkenes and 2-aminopyridines using catalytic amounts of iodine and aqueous hydrogen peroxide as a terminal oxidant.

Graphical abstract: Metal-free synthesis of imidazopyridine from nitroalkene and 2-aminopyridine in the presence of a catalytic amount of iodine and aqueous hydrogen peroxide

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Publication details

The article was received on 21 Nov 2014, accepted on 23 Dec 2014 and first published on 05 Jan 2015


Article type: Communication
DOI: 10.1039/C4RA14970J
RSC Adv., 2015,5, 9591-9593

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    Metal-free synthesis of imidazopyridine from nitroalkene and 2-aminopyridine in the presence of a catalytic amount of iodine and aqueous hydrogen peroxide

    Y. Tachikawa, Y. Nagasawa, S. Furuhashi, L. Cui, E. Yamaguchi, N. Tada, T. Miura and A. Itoh, RSC Adv., 2015, 5, 9591
    DOI: 10.1039/C4RA14970J

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