Jump to main content
Jump to site search

Issue 45, 2015
Previous Article Next Article

Injectable hydrogels based on poly(ethylene glycol) and derivatives as functional biomaterials

Author affiliations

Abstract

Hydrogels based on poly(ethylene glycol) (PEG) and derivatives have attracted significant interest in recent years given their capacity to be well-tolerated in vivo in the context of drug delivery and tissue engineering applications. Injectable, in situ-gelling analogues of such hydrogels offer the additional advantages of being easy and non-invasive to administer via the injection of low-viscosity precursor polymer solutions, expanding their scope of potential applications. In this highlight, we first review the design criteria associated with the rational design of in situ-gelling hydrogels for in vivo applications. We then discuss recent progress in the design of injectable PEG hydrogels, specifically highlighting our ongoing work on PEG-analogue hydrogels based on poly(oligoethylene glycol methacrylate) for targeted biomedical applications.

Graphical abstract: Injectable hydrogels based on poly(ethylene glycol) and derivatives as functional biomaterials

Back to tab navigation

Article information


Submitted
01 Nov 2014
Accepted
10 Apr 2015
First published
13 Apr 2015

RSC Adv., 2015,5, 35469-35486
Article type
Review Article
Author version available

Injectable hydrogels based on poly(ethylene glycol) and derivatives as functional biomaterials

E. Bakaic, N. M. B. Smeets and T. Hoare, RSC Adv., 2015, 5, 35469
DOI: 10.1039/C4RA13581D

Social activity

Search articles by author

Spotlight

Advertisements