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Issue 26, 2015
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Benzyllithiums bearing aldehyde carbonyl groups. A flash chemistry approach

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Abstract

Reductive lithiation of benzyl halides bearing aldehyde carbonyl groups followed by reaction with subsequently added electrophiles was successfully accomplished without affecting the carbonyl groups by taking advantage of short residence times in flow microreactors.

Graphical abstract: Benzyllithiums bearing aldehyde carbonyl groups. A flash chemistry approach

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Publication details

The article was received on 12 May 2015, accepted on 21 May 2015 and first published on 09 Jun 2015


Article type: Communication
DOI: 10.1039/C5OB00958H
Org. Biomol. Chem., 2015,13, 7140-7145
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    Benzyllithiums bearing aldehyde carbonyl groups. A flash chemistry approach

    A. Nagaki, Y. Tsuchihashi, S. Haraki and J. Yoshida, Org. Biomol. Chem., 2015, 13, 7140
    DOI: 10.1039/C5OB00958H

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