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Issue 21, 2015

DNA hydrogel delivery vehicle for light-triggered and synergistic cancer therapy

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Abstract

A DNA hydrogel is reported as a delivery vehicle for gold nanorods and doxorubicin. The two photothermal and chemo cancer agents were co-loaded using electrostatic and DNA binding interactions, respectively. Light-triggered and highly synergistic combination cancer therapy was demonstrated in cellular and animal models.

Graphical abstract: DNA hydrogel delivery vehicle for light-triggered and synergistic cancer therapy

Supplementary files

Article information


Submitted
06 Feb 2015
Accepted
21 Apr 2015
First published
11 May 2015

This article is Open Access

Nanoscale, 2015,7, 9433-9437
Article type
Communication
Author version available

DNA hydrogel delivery vehicle for light-triggered and synergistic cancer therapy

J. Song, K. Im, S. Hwang, J. Hur, J. Nam, G. Ahn, S. Hwang, S. Kim and N. Park, Nanoscale, 2015, 7, 9433 DOI: 10.1039/C5NR00858A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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